%0 Journal Article %T TimEHR: Image-Based Time Series Generation for Electronic Health Records %V 29 %N 12 %P 9170-9180 %W https://infoscience.epfl.ch/entities/publication/0b042ae8-fd8c-40fd-8b29-32a70b82172d %U https://ieeexplore.ieee.org/document/11027528 %X Time series in Electronic Health Records (EHRs) present unique challenges for generative models, such as irregular sampling, missing values, and high dimensionality. In this paper, we propose a novel generative adversarial network (GAN) model, TimEHR, to generate time series data from EHRs. In particular, TimEHR treats time series as images by using 2D convolutional kernels and is based on two conditional GANs. The first GAN generates missingness patterns, and the second GAN generates time series values based on the missingness pattern. Experimental results on three real-world EHR datasets show that TimEHR outperforms state-of-the-art methods in terms of fidelity, utility, and privacy metrics. %J IEEE Journal of Biomedical and Health Informatics %A Karami, Hojjat %A Hartley, Mary-Anne %A Atienza, David %A Ionescu, Anisoara %D 2025-12 %K Convolutional neural nets Convolutional neural networks Data privacy Electronic health records (EHRs) Electronic medical records Generative adversarial networks Irregularly sampled time series Mathematical models Metadata Predictive models Time series analysis Time series generation scientific-publication